20100006009 CASE PRESENTATION

LONG  CASE 

30/F,homemaker,unmarried, hailing from chityal, who completed her bsc botany came with 

COMPLAINTS :-

 Lethargy-----> since 6 months

HISTORY OF PRESENT ILLNESS :-

Patient was apparently asymptomatic 6 months back then she had insidious onset of lethargy, 

easy fatiguability on doing daily chores like cooking, cleaning the house.

No history of any fever, cough,Loss of appetitie,weight loss,chest pain, palpitations,pedal edema

No menstural abnormalities

PAST HISTORY :-

At her 17years of age(in year 2010),One afternoon while bathing, she suddenly developed weakness 

of right upper limb and lower limb, along with deviation of mouth to left side upon which she made 

sounds , her  mother who was nearby came to her aid ,and she was taken to hospital in nalgonda 

within an hour,and referred to gandhi hospital where she was admitted for 1month,during which her 

speech returned.She was able to walk without support after 1month,but still has limp on walking.

Weakness of the right upper limb persisted,like unable to lift the hand,hold objects, stretch out.

This episode was not associated with blurring of vision, vomiting,headache,loss of consciousness tingling ,numbness, involuntary movements, swallowing difficulty.

4 years back in 2019 she presented to Kamineni narketpally with complaints of painful swelling 

in the left side of the neck, for which usg guided fnac was done showing caseating 

 granuloma,started on ATT  and used for 6 months.

No h/o hypertension,diabetes,thyroid disorders,coronary artery disease.

FAMILY HISTORY:-

No similar complaints in the family.she has one elder and one younger sister


PERSONAL HISTORY:-

Appetite is normal, diet consists of lentils,rice, vegetables, less of meat,eggs ,fruits.


GENERAL EXAMINATION :-

Patient is conscious, coherent,co-operative.Moderately built and nourished

Pallor +

Icterus -

Cyanosis -

Clubbing -

Lymphadenopathy + :posterior cervical ,lymph node ,mobile,non tender 

-Contracture present at the right metacarpophalangeal joint.

VITALS :

Pulse:-90/min,right arm,regular rhythm,normal volume

Arteries                       Right.                                Left

Carotid.                         +                                        + 

Subclavian.                   +.                                     absent

Brachial.                       +.                                     absent

Radial.                           +.                                     absent

Femoral.                       +.                                     +

Popliteal.                      +.                                    +

Posterior tibialis.          +.                                    +

Dorsalis pedis.             +.                                     +

Radio femoral delay.   not present

Bruit: heard over right and left carotid artery















Blood pressure                 Right                       Left

upper limb                    120/60mmhg.              not recordable

lowerlimb.                    100 mmhg systolic.     100 mmhg


Respiratory rate-22cycles per min

JVP-Not elevated

Grbs-120mg/dl


SYSTEMIC EXAMINATION

CENTRAL NERVOUS SYSTEM

Right/left handed person :initially right,then learnt to write with left hand since 12 years

Education:Bsc botany

HIGHER MENTAL FUNCTIONS :conscious,oriented

Memory: intact (immediate,recent,remote)

Speech:

comprehension:+

fluency+

repetition+

reading+

writing+

naming objects+


CRANIAL NERVES.       Right.                       Left

1-olfactory:                    present.                 present

2-visual acuity:              normal.                  normal

            Visual field:confrontation method:normal

            Colour vision:normal

            Fundus:             normal.                normal.

3,4,6

eyelids :.                             normal.          normal

position of eyeball at rest: normal.          normal

extraocular movements :.  normal.          normal 

pupil :size,shape               normal.         normal 

direct and indirect light reflex: present.   present


5:

sensory:          touch.              present.                   present

                        pain.                present.                  present

                        temperature.    present.                 present 

motor: side to side jaw movement  normal

reflexes:         corneal.           present.                present

                       jaw jerk.          present.                present

7th- 

motor-       frontalis.                normal.                    normal

                  orbicularis oculus: normal.              normal

                 orbicularis oris:    deviated to the left 

                  buccinator:.       decreased.              normal

sensory: taste:.                  normal.                    normal


8th:  Rinnie's.                       normal.                     normal 

        Weber's :No lateralization

9th,10th-

       Position of uvula:central 

       Gag reflex                       present.                      present.

11th-    SCM-.                     normal.                       normal             

            Trapezius-.             normal.                        normal 

12th-

           Tongue: size,symmetry, 

                                           normal.                         normal

MOTOR SYSTEM:

Attitude of limbs:

   Upper limb.

                                              Right                                  Left     

                              Semi- Flexion at elbow                     Normal

                              Semi pronated

                              Thumb tucked into palm

    Lower limb.  

                            Semi -flexed at knee.                    normal

Bulk:arm:

           forearm:.                24cm.                              25cm

           Thigh:.                    38cms.                           39cms.

Tone:                              

           upperlimb.          increased                             normal

           lowerlimb.           increased.                            normal

Power:

1)Neck:.       flexors:.        normal.               normal

                     extension:.  normal.              normal

2) shoulder:  Supraspinatus.   4-/5.                  5/5

                     Deltoid:.            4-/5.                  5/5

                      Infraspinatus:.  4-/5.               5/5

                      Latissimus dorsi :4-/5.         5/5

                      Serratus anterior:  4-/5.        5/5

                       Pectoralis major:.   4-/5.       5/5 

                        Rhomboids  4-/5.                  5/5

3)elbow: biceps.                     4-/5.                  5/5

                 Triceps.                   4-/5.                   5/5

                  Brachioradialis.      Not able to pronate               5/5

4) wrist : flexor carpi radialis     Not   able to flex             5/5

                 flexor carpi ulnaris.     Not   able to flex                         5/5

                 extensor carpi radialis longus: Not able to extend      5/5

                 extensor carpi ulnaris longus.  Not able to extend      5/5

                                extensor digitorium :  Not able to extend     5/5


Handgrip.                                   60%.                                         100%

Abductor pollicis longus.          Not able to abduct                        5/5

Abductor pollicis brevis.         Not able to abduct                           5/5

Extensor pollicis longus.         Not able to extend                          5/5

Extensor pollicis brevis.          Not able to extend                          5/5

Opponens pollicis.                  Not able to perform.                        5/5

Adductor pollicis.                    Not able to adduct                           5/5

Lumbricals                              Not able to Perform                         5/5

Interossei   -dorsal.                Not able to Perform                          5/5

                     palmar.               Not able to Perform                        5/5





5)Trunk:abdominal

                             Beevor's - absent

 6)Hip:   Iliopsoas.                        4+/5.                   5/5 

            Adductor femoris.             4+/5.                   5/5

            Gluteus medius                4+/5.                  5/5

            Gluteus Maximums.         4+/5.                  5/5




7)knee: flexion: hamstrings.    4+/5.              5/5

            extension: quadriceps 4+/5.             5/5



7) Ankle:      Plantar flexion:.             Not able to perform              5/5

                     Dorsiflexion:.                Not able to perform             5/5



Reflexes:

Superficial

corneal.                                    present.                    present

abdominal.                             present.                    present

plantar:.                                   extensor.                  flexion


Deep

Right upper limb Reflexes

Knee reflex

biceps.                                     3+.                                     2+

supinator.                                3+.                                    2+

triceps.                                     3+.                                    2+

knee jerk.                                3+.                                    2+

ankle jerk.                               +1.                                     +1

No clonus


Sensory:. in all dermatomes

fine touch.                           present.                           present 

joint position.                       present.                          present 

vibration.                              present.                          present

crude touch.                        present.                          present

pain.                                   present.                            present

temperature.                      present.                            present


Romberg's test: negative(no sway)

cerebellum:

finger nose.                      Not able to perform                       normal

finger finger.                     Not able to perform                       normal

knee heal.                           normal.                                       normal

rebound phenomenon- absent

tandem walking.  - normal 


Gait :-Gait Video

circumduction on the right,

Toes touching the ground first

pace:normal

falling to sides:absent

hand swing:.                    absent                           present

turn:.             normal 

Autonomic nervous system:normal

Meningeal signs:absent


CARDIOVASCULAR SYSTEM :

-Elliptical & bilaterally symmetrical chest

-No visible pulsations/engorged veins on the chest

-Apex beat seen in 5th intercostal space medial to mid clavicular line

-S1 S2 heard

-No murmurs

RESPIRATORY SYSTEM

  Upper respiratory tract normal

  Lower respiratory tract :

-Left supraclavicular fullness present



-Trachea is central

-Movements are equal on both sides

-On percussion resonant on all areas

-Bilateral air entry equal

-Normal vesicular breath sounds heard

-No added sounds

-Vocal resonance equal on both sides in all areas

PER ABDOMEN :

-Scaphoid

-No visible pulsations/engorged veins/sinuses

-Soft,non tender, no guarding and rigidity, no organomegaly

-Bowel sounds heard,No abdominal Bruit

PROVISIONAL DIAGNOSIS :
Young onset CVA : Right hemiparesis with Residual weakness of right upper limb with flexion deformity at right wrist

?Takayasu Arteritis

Left cervical Lymphadenopathy(Past history of TB,Used ATT for 6months)

INVESTIGATIONS :

2010

Hb: 7.5gm/dl,TLC-8500 cells/mm3, adequate platelets

Ana:negative

2d echo:normal

Serum creatinine:0.9mg%

GOVT HOSPITAL,HYDERABAD
  19 th january 2010

Previous reports

CT BRAIN(plain):
Hypoensity is seen in left capsulo ganglionic region and parigete temporal lobes with compression over left lateral ventricle.
IMPRESSION: ACUTE LEFT MCA INFARCT.

CAROTID DOPPLER: 


RIGHT CCA:
shows diffuse circumferencial thickening 1.3m causing 30-40% in proximal and mid portion of cca. Causing obstruction and reduced flow velocities.
Distal cca and bulb,both internal and external carotid arteries show thrombosis causing obliteration of lumen 60%.with reduced flow velocities 
LEFT CCA: 
Filled echogenic material s/o thrombus from origin causing NEAR TOTAL obstruction and minimal color flow filling.
The thrombus extending Upto bulb,ICA and ECA causing partial obstruction and reduced flow velocity.

IMPRESSION: B/L CAROTID THROMBOSIS,DIFFUSE ON LEFT SIDE.
b/l vertebral arteries show NORMAL color flow filling and velocities.

CT AORTIC ANGIOGRAM:
Narrowing at origin of inferior mesenteric artery.
-Diffuse narrowing of right common carotid artery.
-There is narrowing of origin of left common carotid artery and no opacification of distal left common carotid artery 
-
Left subclavian artery is normal near the origin.There is diffuse narrowing of subclavian artery distal to origin of vertebral artery.
-E/o collateral seen in left supra scapular region.
-Irregular narrowing of thoracic aorta is seen.

IMPRESSION:Features are suggestive of AORTOARTERITIS.




27th September 2019,Private hospital 
Esr: 15mm/hr(normal)
Swelling over left posterior side of neck
Fnac IMPRESSION:Features are in favor of Granulomatous Lymphadenitis possible of T.B etiology.    
 
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SHORT  CASE I 
 

CHEIF COMPLAINTS 

55yr male Tiles construction worker came with complaint of

Generalised weakness :- 2 months

                         Fever  :- 2 months

                 Dry cough  :-2 months                        

HISTORY OF PRESENT ILLNESS 

Patient was apparently alright till 2months back then he had insidious onset of fever, intermittent, relived on taking medications,not associated with chills and rigors.

Fever is associated with generalised weakness(not able to perform his previous routine job works) and dry cough(which is insidious onset, intermittent,relived on taking medication, no aggravating factors, not associated with positional or seasonal variation)

History of weight loss, loss of appetite present.

No history of coughing of blood, chest pain, palpitations,swelling of lower limbs, facial puffiness, decreased urine output

PAST HISTORY

History of pulmonary tuberculosis 25years back,used ATT for 6months.No history of interventional procedures done during that period.

Not a known case of DM/HTN/CAD/CVA/EPILEPSY/Thyroid disorder/Retroviral illness

PERSONAL HISTORY

Takes alcohol 90ml whisky per day for past 30years

Tobacco chewer for 30years

Takes mixed diet,appetite decreased from past 2months,regular bowel and bladder movements,adequate sleep

FAMILY HISTORY

No history of similar illness in the family

GENERAL EXAMINATION

Patient is conscious, coherent,co-operative

Moderately built and nourished

No Pallor,Icterus,Cyanosis,Clubbing,Lymphadenopathy,Pedal edema

Oral candidiasis +

Spine deformity-Dorsal thoracic vertebra Gibbs +

VITALS :-

PR:-80bpm,regular rhythm,normal volume, all peripheral pulses felt

BP-110/80mmhg,In right upper limb sitting position

RR-28/min,Abdominothoracic type, regular 

Temperature:99 F

SPO2 : 99% on Room air

Grbs-120mg/dl

JVP-Not elevated










SYSTEMIC EXAMINATION

RESPIRATORY SYSTEM

Upper respiratory tract :

     Nose--external nose normal, no deviated nasal septum

     Oral cavity--Poor oral hygiene,Oral thrush +

Lower respiratory tract :

  Inspection :

-Trachea appears to be in centre

-No scars, sinuses,dilated veins over the chest

-Apical impulse not visible

-Chest-Bilaterally symmetrical/Elliptical

-Chest movement Decreased on right side

-On examining back of the chest in standing position, with arms hanging by the side of the body

      No drooping of shoulder

      Spinal deformity present -->Dorsal thorassic vertebrae Gibbus +

Palpation :

-Trachea--Central



-Apex beat--1.5cm medial to mid clavicular line in the left 5th intercostal space

-Respiratory movements --decreased on right side with respiration

-Chest Measurements :

       Anteroposterior diameter-18cm

               Transverse diameter-28cm

     Ratio of AP diameter : Transverse diameter :



       Chest circumference :85cm

       Vocal fremitus  : Increased on right side of chest

Percussion : Resonant

Auscultation:

Supraclavicular & Infraclavicular : Bronchial breath sounds +

Vocal Resonance:increased on right side of chest


Added sounds :

Inspiratory crepts present on the right side of chest

OTHER SYSTEM EXAMINATION

CARDIOVASCULAR:

-Elliptical & bilaterally symmetrical chest

-No visible pulsations/engorged veins on the chest

-Apex beat seen in 5th intercostal space medial to mid clavicular line

-S1 S2 heard

-No murmurs

PER ABDOMEN :

-Scaphoid

-No visible pulsations/engorged veins/sinuses

-Soft,non tender, no guarding and rigidity, no organomegaly

-Bowel sounds heard

CENTRAL NERVOUS SYSTEM

-Higher mental functions intact

-Cranial nerves - intact


-Sensory system-normal


-Motor system -normal

 PROVISIONAL DIAGNOSIS :          

?Re-activation of pulmonary Tuberculosis

INVESTIGATIONS

Radiological






BLOOD

CBP

    Hb-10.4gm/dl

    TLC -5400cells/cumm

     Plt - 1.98lakhs/cumm

LFT

   TB-1.2 mg/dl

   DB-0.3 mg/dl

   AST-88 IU/L

  ALT-72 IU/L

  ALP-553 IU/L

    TP-8.3gm/dl

  ALB-2.9gm/dl

RFT

  Sr Na/k/cl--133/4.3/96

  Sr cr-1.2mg/dl

  Sr urea-41mg/dl

RBS-94mg/dl

Serology

HIV 1/2  Rapid test --->Reactive


Sputum for AFB & CBNAAT : Negative


FINAL DIAGNOSIS :

?Reactivation of Pulmonary Tuberculosis

Newly Detected Retrovirus illness

Osteoporotic Fracture of dorsal thoracic vertebrae

Bronchiectasis(?Past TB Sequlae)


--------------------------------------------------------------------------------------------------------------------------------------
 
SHORT CASE II 
 

 CHEIF COMPLAINTS

40yr female farmer by occupation came with complaint of 

Pain in the both hips (Since 6 months)

Pain in the both hands Finger joints on & off (Since 6months)

HISTORY OF PRESENT ILLNES

Patient was apparently alright 6months back,then she developed pain in the both hip regions which is insidious onset,gradually progressive,aggrevated on walking,getting up from sitting posture,Pain relived on taking medications.

Associated with Pains in the multiple small joints of both hands on and off.No history of early morning stiffness,heel pain.

PAST HISTORY

Patient had history of multiple hospital  admissions due to hypokalemic paralysis over past 3years

1st episode :-In 2020,Pt developed weakness of right lower limb, taken to hospital found out to be potassium low, after correction, she recovered 

Asymptomatic between

2nd episode :-In NOV 2021,Paraperesis,Potassium was low,Recovered after correction

3rd episode : In May 2022,Quadriparesis,Potassium was low,Intubated and connected to ventilator in view of respiratory paralysis.Discharged after 7days

4 Months back patient had burning sensation of both eyes which is aggravated on watching TV,cellphone and excessive thirst(bcz of drying of tongue) associated with left parotid gland swelling.With these symptoms patient came to the hospital, eye examination revealed severe dry eye.In view of connective tissue disorder(?sjogren syndrome), Lower lip biopsy was done.Histopathology report shows lymphocytic infiltration of minor salivary glands



DRUG HISTORY

Patient is started on prednisolone tablets 4months back.She used regularly for 1month then after only during severe pains

FAMILY HISTORY

No similar complaints in the family members

PERSONAL HISTORY

Takes mixed diet,appetite normal,regular bowel and bladder movements,adequate sleep.No addictions

GENERAL EXAMINATION

Patient is conscious, coherent,co-operative.Moderately built and Moderately nourished.

Blood pressure-130/70mmhg,right arm, supine position

Pulse-90/min,regular rythm,normal volume, all peripheral pulses felt

Respiratory rate-20/min

Temperature-98 F

Spo2-98% on room air

Grbs-125mg/dl

No pallor,icterus,clubbing,cyanosis,lymphedenopathy,edema of legs

No raised JVP


HEAD TO TOE EXAMINATION

General Condition - Moderately built and Moderately nourished.

Hair - Thin and slightly greyed. Not easily pluckable or no areas of scarring or non-scarring hair loss. No lesions noted on the scalp.

Eyes - No conjunctival chemosis or injection, No redness or corneal lesions. 

General Head, Neck & ENT - No abnormalities. No lymph node enlargement.

Axial - No apparent spinal deformities

Fingers and Nails - No clubbing or cyanosis.Right little finger shows Flexion at the PIP joint




MUSCULOSKELETAL SYSTEM EXAMINATION

Appendicular Skeleton-Upper limb

Shoulder joint(Both sides)
          1)No tenderness or swelling over the both shoulder joint


                2)Apprehension Test--->Negative

Elbow Joint(both sides)
       No tenderness or swelling over the both elbow joint

Wrist Joint(both sides)
       1)Two thumb technique---No tenderness or swelling
          2)Wrist Flexion and Extension---No tenderness


MCP joint(both sides) 
          1)Squeeze Technique---No tenderness

             2)Applying pressure to joint---No tenderness


Interphalangeal Joint
               1)Four Finger Technique---Tenderness present in the Right 2nd finger PIP joint


APPENDICULAR SKELETON-LOWER LIMBS

Hip joint(both sides)
              1)Trendelenburg Test :-Trendelenburg sign positive both sides of hip


Knee joint(both sides)
                  1)Palpation of knee joint---No tenderness 
Ankle Joint(both sides)
                1)Palpation of bare area of ankle joint---No tenderness

Achilles Tendon(both sides) : No swelling or tenderness

Metatarsophalangeal joint(Both sides)
                    1)Squeeze Technique : No Tenderness


Axial Skeleton
Inspection - No visibly apparent spinal deformities; 

Palpation - Inspectory findings confirmed. No spine tenderness. 

Movements - Atlanto-occipital - Flexion, extension and lateral flexion normal
                      Atlanto-axial - Rotation of head normal
                      Spinal Flexion, Spinal Extension, Lateral Flexion and Rotation are normal

1)Straight leg raising test ---No tenderness

2)Patrick's test
               Mild tenderness in the right side noted    

3)Gaenslen Maneuver ---No tenderness seen


4)Schober's test 

EXAMINATIOIN OF OTHER JOINTS :

1)Temporomandibular Joint---No tenderness, synovial thickening, crepitus

2)Sternoclavicular Joint---No tenderness

EXAMINATION OF OTHER SYSTEMS :

CARDIOVASCULAR SYSTEM

-Elliptical & bilaterally symmetrical chest

-No visible pulsations/engorged veins on the chest

-Apex beat seen in 5th intercostal space medial to mid clavicular line

-S1 S2 heard

-No murmurs

PER ABDOMEN :

-Scaphoid

-No visible pulsations/engorged veins/sinuses

-Soft,non tender, no guarding and rigidity, no organomegaly

-Bowel sounds heard

CENTRAL NERVOUS SYSTEM

-Higher mental functions intact

-Cranial nerves - intact


-Sensory system-normal


-Motor system -normal


-Gait --- Waddling Giat + 

   Gait video


PROVISIONAL DIAGNOSIS

Primary Sjogren  Syndrome 
 
Spondyloarthropathy

Hypokalemic Periodic Paralysis

INVESTIGATIONS

 Chest x ray

     



X ray B/L wrist 




 X ray pelvis


ECG


Hemogram

HB - 8.0gm/dl
Total count - 7,500
Neutrophil - 62
Lymphocytes - 28
Eosinophil - 02
Monocytes - 08
Basophils -00
PCV -26.6
MCV- 80.4
MCH- 24.2
MCHC - 30.1
RDW cv  - 21.6
RBC count - 3.31million/cumm
Platelets - 2.56 L/cu mm

RBS - 101mg/dl


CUE 

PH - 7.0

Color - pale yellow

Appearance - clear

Reaction - acidic

Specific gravity -1.01

Albumin - trace

Sugars - nil

Bile salts - nil

Bile pigments - nil

Pus cells  : 3-4

Epithelial cells : 2- 3

RBC - nil

Crystals - nil

Casts - nil


RFT 

Urea - 16mg/dl

Creatinine - 1.3mg/dl

Uric acid - 3.1 mg/dl

Calcium - 10.1mg/dl

Phosphorus - 2.6mg/dl

Sodium - 141mEq/L

Potassium - 3.6 mEq/L

Chloride - 105 mEq/L


LFT

Total bilirubin - 0.67mg/dl

Direct bilirubin - 0.12mg/dl

SGOT - 14 IU/L

SGPT -11 IU/L

Alkaline phosphatase - 492 IU/L

Total proteins - 6.6 gm/dl

Albumin- 4.02gm/dl

A/G ratio 1.56


ESR - 30mm/ 1st hour

ABG
    PH------>7.22
    Pco2---->24.2
    Po2------>98
    Hco3----->9.7

FINAL DIAGNOSIS
Primary Sjogren  Syndrome 
 
Spondyloarthropathy

Microcytic Hypochromic Anemia(?Nutritional)

Hypokalemic Periodic Paralysis

Distal Renal tubular Acidosis
  


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